Cultures around the world have used Aloe vera for medicinal reasons since the beginning of recorded history. More than $85 million dollars has gone into researching this remarkable molecule. That makes it the most-researched plant in the world.

The problem is that its active ingredient denatures within days of extraction. This very short shelf-life explains why modern Aloe vera products can’t offer the same results as those recorded in ancient times, when only fresh Aloe was used.

In the 1980s, scientists discovered the active molecule in fresh Aloe vera gel and named it Acemannan. They also discovered a way to stabilize this molecule for commercial use.

Validated in over 700 published studies as nature’s most powerful immune-modulating agent, Acemannan is mostly made of mannose, is needed for proper cellular function. Acemannan also has antifungal, antibacterial, antiviral, and anti-inflammatory benefits.

Research also showed it helps activate and balance gut macrophages, an essential part of our immune system. Since about 70-80% of a person’s immune system lives in the gut, this research caused a huge consumer demand for stabilized Acemannan.

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[Acemannan Aloe] Acemannan is a complex polysaccharide found in the inner leaf gel of the aloe plant. A specialized cell called a leucoplast produces the acemannan. It’s composed of mannose, glucose, and galactose monomers making it into a polysaccharide. Acemannan is the specific component that sets Aloe Vera apart from the 400 other species of aloe plants. Acemannan contains many nutritional qualities.


Scientific research has shown that Acemannan is useful for a host of issues, including those related to the immune and digestive systems. Below is a list of all the benefits of Acemannan:

  • Helps cells to be more resistant to viruses and pathogenic bacteria
  • Improves overall cellular metabolism and functioning
  • Promotes healthy inflammation response
  • Provides critical lubrication of joints
  • Aids in the absorption of water, minerals, and nutrients in the GI tract
  • Reduces pain
  • Improves vascular flow​
  • Increases the body’s own production of interferon, interleukins
  • Increase the number of antibody forming T-cells in the spleen
  • Increases the number and activity of killer T-cell and increase monocyte activity
  • Soothes and promotes healing of intestinal disorders such as indigestion, heartburn, hyper-acidity, peptic and udodenal ulcers, colitis, and hemorrhoids
  • Promotes healthy kidney function
  • Speeds wound healing
  • Reduces allergic reactions
  • Stimulates bone marrow activity
  • Anti-aging properties
  • Supports healthy blood pressure